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Top 5 Best Antiseptic Wipes for Dogs

Antiseptic and antibacterial wipes are the only safe way to treat a dog's wounds, fungal and bacterial infections, hot spots and pet acne.


The best antiseptic wipes for dogs can be used to treat fungal and bacterial skin infections like hot spots and acne in our canine companions. They make it fast and easy to care for our pets. The only thing you need to make sure is to choose a wipe that is specifically made for dogs. Do not use any antiseptic wipes that were designed for people as they may be toxic to dogs.

Top Best Antiseptic Wipes for Dogs to Treat Fungal & Bacterial InfectionsA dog's skin is much more sensitive than ours. So aside from containing dangerous ingredients, using antibacterial wipes formulated for humans on your pet could actually make his skin condition worse.

The reason for this is because dog's skin has a different pH than ours. For people, a normal skin pH range is approximately 5.2 to 6.2 (which is more acidic) [study], while for canines – and this usually depends on the breed, age and size of a dog – their skin pH levels range from 5.5 to 7.5 (that's more alkaline) [study].

This means that using human products like shampoo on dogs will dry out their skin and cause more irritation and further skin problems. The same applies to wipes and dog grooming supplies. Here are five best antiseptic wipes for dogs:

* Click on the antiseptic dog wipe for more information and prices. Alternatively, scroll down below for more details.

Why use antibacterial/antiseptic wipes for dogs?

Unlike regular dog grooming wipes, antibacterial wipes for dogs serve a different purpose.

It's no secret that dogs like to stick their noses everywhere and attract all kinds of nasty parasites, fungi, bacteria and more. Pyodermas, malassezia, itching, yeasty formation, and other fungal and bacterial conditions are commonly found on dog’s skin and in skin folds.

These conditions have been the source of endless woes among pet owners. Using best antiseptic wipes for dogs is a great solution for most topical skin conditions. Vets strongly suggest including some of the best antiseptic wipes for dogs in your pet's first aid kit.

However, if your pooch already has a serious condition, it's too late for pads – make sure to have him checked out by a veterinarian in case there is an underlying health condition.

Best Antiseptic Wipes for Dogs to Treat Fungal & Bacterial Infections

What are the Best Antiseptic Wipes for Dogs?
For treating dog's fungal and bacterial skin infections

1Sogeval Douxo Chlorhexidine 3-Percent PS Pads

Sogeval Douxo Chlorhexidine 3-Percent PS PadsThese medicated wipes for dogs from Sogeval Douxo will surely help clean any topical skin condition that your pet presents with. It prevents irritations and bacterial growth on the pet’s skin, which is prone to these issues. The wipes have been proven effective as an antiseptic cleanser for the dog’s inner-digital areas, genitalia, nasal or lip pyodermas, chin acne lesions and tear stains or heavy motes.

These best antiseptic wipes for dogs are safe for long-term use and gentle on the skin. Satisfied purchasers and veterinarians recommend these pads on wiping dog’s face and paw folds, as well as wiping urine off the dog’s genital area to prevent infection and bacteria from entering through the urethra. They found these pads really awesome in cleaning skin areas that need special attention.

Consumers say that Sogeval Douxo Chlorhexidine 3-Percent PS Pads for dogs get the job done, are very handy, smell so nice that dogs don’t evade them when wiped down, and they’re also very gentle. They say they don't cause redness or irritation like the other brands they’ve used previously on their pets.

Read the label carefully. A customer who misread thought that he was getting the 50-count thinner pads. He felt that the wipes in this 30-count pack are way too thick and a bit coarse for his pup. He had to cut the pads in half and use half a pad at a time. Nevertheless, he’s happy with the outcome of these medicated pet wipes as it gets the job done effectively by applying it twice daily over areas that need the most attention.


  • Proven effective as an antiseptic cleanser
  • Gentle on skin
  • Safe for long-term use

  • One consumer noted that the wipes in the 30-count pack are thicker than the wipes in the 50-count pack. He cut the 30-count wipes in half

best antiseptic wipes for dogsMost helpful dog owner’s review (read the full Amazon review): “As a long-time bulldog owner, I have always had Malaceb pads handy – bulldog's skin requires some attention. However, after hearing there were some problems with the manufacturer, I followed vet's recommendation…”


2Pet MD – Chlorhexidine Wipes with Ketoconazole and Aloe

Pet MD – Chlorhexidine Wipes with Ketoconazole and AloeThese incredibly easy-to-use pads from Pet MD are the perfect solution for relieving pets’ fungal and bacterial conditions, skin infections, superficial cuts or wounds, and insect bites. The wipe deodorizes and dries up skin irritations, too, making the affected area less vulnerable to infections. These wipes are especially good in such delicate areas as the face and paw folds, underarm, and groin.

Each wipe contains both active and inactive ingredients – 2% chlorhexidine and 1% ketoconazole in an alcohol-based solution, along with aloe, leaf juice and many others – that kill bacteria and yeast usually associated with skin infections in pets. Buyers are pleased with these wipes because of their efficiency in treating and healing, and even preventing, various fungal and bacterial infections.

Pet owners who purchased Pet MD – Chlorhexidine Wipes with Ketoconazole and Aloe found the medicated swabs really effective in curing chronic staphylococcus infections on their pets. Others believe they helped relieve severe itchiness and other allergies without burning their dog’s skin.

What are the Best Antiseptic Wipes for DogsA few buyers thought these wet wipes could have been much bigger and thicker so they covered more area. On the whole, the convenience and usefulness of these wipes against bacterial and fungal infections are what make customers queue up for more. It also counts a lot to customers that this non-stinging topical solution is made in the USA.


  • Deodorizes and dries up skin conditions
  • Contains 2% chlorhexidine and 1% ketoconazole in an alcohol-based solution
  • Buyers found these best antiseptic wipes for dogs effective in curing chronic staphylococcus infections
  • Made in the USA

  • Some buyers noted that these wipes were smaller than they had hoped 

best antiseptic wipes for dogsMost helpful dog owner’s review (read the full Amazon review): “Buy your furbaby some of these!! These wipes are awesome for toe chewers! My vet recommended this type of wipe and boy, was she right on the money! My girl has seasonal allergies and chews her toes…”


3Mal-A-Ket Wipes by DermaPet

Mal-A-Ket Wipes by DermaPetIf your pets are suffering from loads of skin problems, DermaPets’s Mal-A-Ket wet wipes just might be the right solution. These pre-moistened antiseptic cleansing wipes use acetic acid, ketoconazole, chlorhexidine gluconate, aloe, and pyodermic ingredients to combat bacterial, microbial, and fungal infections.

Their astringent features greatly help in keeping all affected areas clean and dry. Customers use these medicated, yet gentle, wipes for various regimens. They find it indispensable after each bath or shampoo, after their pets pee or go to the potty, in wiping motes off their pets’ faces, and for overall general hygiene.

For most buyers they have made a great difference in handling skin infection and allergies, as well as in preventing its recurrence. Pet owners are totally convinced that Mal-A-Ket Wipes by DermaPet work well and gets the job done.

Possibly an isolated case, one customer reports about his dog getting skin irritations after a single night of applying this product. So he urges other buyers to first test it on just one spot on their dog overnight to see if there’s any bad reaction. This is a valid observation and is recommended for any of the best antiseptic wipes for dogs that owners introduce to their pets for the first time.


  • Contain acetic acid, ketoconazole, chlorhexidine gluconate, aloe, and pyodermic ingredients
  • Buyers noted that these wipes helped treat skin conditions and prevent them from coming back

  • One consumer noted that these best antiseptic wipes for dogs irritated his pet's skin

best antiseptic wipes for dogsMost helpful dog owner’s review (read the full Amazon review): “These wipes are great. I have a bull mastiff who gets infections in between the pads of her paws w every season change. We have tried meds , tri- otic , Epsom salts and these wipes are hands down the best…”


4Keto Hex Wipes

Keto Hex WipesThese wipes from Vet One are more affordable, yet highly effective. Consumers say they work better than many of the other best antiseptic wipes for dogs that they've tried. The individual sheet is thin and ideal for wiping smaller paws. They contain effective ingredients to fight against various fungal and bacterial ailments in pets that even include horses.

They're also effective for antiseptic cleansing of face and finger folds, including the armpit and groin areas. Each wipe contains 20 mg chlorhexidine, 17 mg ketoconazole, and other effective ingredients in an alcohol-based solution for better cleansing power. They come highly sterilized with no strong and unpleasant smell that often puts dogs off.

The majority of users are one in praising Keto Hex Wipes for their healing abilities against various pet infections, including oozing skin sores and yeast problems, especially for pets approaching the twilight years. These users usually found out that when used at least twice daily on their pets, infections clear up quickly. After which, a daily wipe usually suffices as preventive care.

While others like that the wipes are thinner allowing them easy access to tight folds, a few users would have preferred thicker and larger sheets to cover larger infected areas more quickly. They think that thicker wipes could cleanse better and remove more filth in just one pass. Nonetheless, they recommend Keto Hex Wipes for their affordability and effectiveness in providing healthy pet skin and coat in spite of their thinness.


  • Effective for many different types of animals including cats, dogs and horses
  • Contain 20 mg chlorhexidine and 17 mg ketoconazole
  • No strong smell that might upset your pet

  • Some users noted that they would prefer a larger, thicker wipe

best antiseptic wipes for dogsMost helpful dog owner’s review (read the full Amazon review): “I've bought (and been satisfied) with Ketoseb brand, Douxo, and now these. I like these because 50 thin ones come in a container, whereas the Douxo were 30 thicker ones. For my purposes, more thinner ones is better. Both…”


5Dechra TrizCHLOR 4 Pet Wipes

Dechra TrizCHLOR 4 Pet WipesCost-wise, these 50-count pads are the cheapest in our line of choices for the best antiseptic wipes for dogs. Each pad from Dechra uses chlorhexidine gluconate and TrizEDTA, which poss both antibiotic and antimicrobial features to boost healthier pet skin. They also fight infections and other skin issues before they can make matters worse.

These wipes are especially formulated for dogs and cats and are perfect as antiseptic cleansing of pet’s face and paw folds, underarm, and groin area. The wipes are thin and gentle on the pet’s skin and does not cause any redness, irritation or itchiness. Customers find them very affordable and effective.

Their efficacy has been well proven by customers. Some owners say their pets were saved by these wipes from more serious procedures, such as painful biopsies and surgery for severe allergies and acute rashes. Dechra TrizCHLOR 4 Pet Wipes have treated serious conditions that did not respond properly to various prescription medicines. Compared to those costly and excruciating procedures and medications, resorting to these simple wipes turned first-time buyers into loyal patrons!

A common feedback is the wipe’s thinness which makes separating the pads an extremely meticulous task. One user says they're so paper thin that he inadvertently uses two to three pads at a time. In general, however, customers find that to be unimportant. They totally love these pads, not only because they’re downright cheap but also because they work perfectly on their pets.


  • Contain chlorhexidine, gluconate and TrizEDTA
  • Formulated for use with cats and dogs
  • Gentle on skin
  • Some buyers noted that these wipes saved their pets from having to undergo costly surgeries

  • Many buyers complain that these best antiseptic wipes for dogs are too thin

best antiseptic wipes for dogsMost helpful dog owner’s review (read the full Amazon review): “My French Bulldog has severe allergies and developed a horrible rash on the inside of her hind legs. No matter what my vet prescribed, the rash just wouldn't clear up. She was ready to do biopsies on the rash when…”

Need to clean a dog wound?

If you're looking for ways to clean a dog wound, not all antibacterial dog wipes will work or should even be used for that. I recommend you watch our video below on how to clean a dog wound and read the full guide for more advice on using antiseptic wipes of that.

FULL GUIDE: How to Safely Clean a Dog Wound

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