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Flea treatments are a necessity for protecting our dogs from a range of diseases carried and passed on by fleas. But with so many options on the market it’s hard to know which is the best flea treatment for dogs. We've tested many, some have been ineffective while others while very effective may be dangerous to pets.

Moreover, studies found that fleas develop insecticide resistance and poorly designed flea treatments become ineffective quickly. The best flea treatment for dogs should have a long-lasting formulation to prevent that resistance, as well as be safe for dogs.

Best Flea Treatments for DogsThe first step you should take when you notice a flea infestation is to consult your veterinarian. They will likely have multiple suggestions for the best flea treatment for dogs, and they can also guide on how to prevent fleas in the future. For more tips on getting rid of fleas on a dog, watch this video guide.

It is extremely important to get rid of fleas as soon as you find them on your pet. Fleas will not go away on their own. If left untreated, a flea infestation could lead to hair loss, inflammation, a secondary skin infection or anemia in dogs. Below is the list of most popular best flea treatment for dogs that most pet owners found effective and safe.

COMPARISON: 3 Best Flea & Tick Treatments Compared – Frontline vs. Seresto vs. Vet's Best

50 Best Flea Treatment for Dogs Options
(as rated and chosen by pet owners)

Best Flea Treatments for Dogs1. Only Natural Pet EasyDefense Shampoo

Price: $21.98Only Natural Pet EasyDefense Flea & Tick Shampoo

An affordable all-natural solution to flea and tick defense, the Only Natural Pet EasyDefense shampoo uses botanical ingredients to repel fleas, ticks, flea eggs, and flea larvae. This product offers year-round protection without any DEET, pyrethrins, or synthetic pesticides, harsh chemicals or sulfates. Only Natural Pet provides a 100% satisfaction guarantee on this product.

2. Only Natural Pet EasyDefense Spray

Price: $12.99Only Natural Pet EasyDefense Flea And Tick Spray

An alternative application method of the EasyDefense flea and tick defense solution from Only Natural Pet, this best flea treatment for dogs contains the same all-natural ingredients as the shampoo above. The easy to use spray format means that you can spray your dog’s fur as well as pet bedding, carpets, rugs, upholstery, and drapes. This Only Natural Pet spray also comes with a 100% satisfaction guarantee.

3. K9 Advantix II Flea, Tick Prevention

Price: $27.99K9 Advantix II Flea, Tick and Mosquito Prevention

K9 Advantix II Flea, Tick and Mosquito Prevention is a product of Bayer Animal Health. Waterproof and vet recommended, this is a flea and tick preventative as well as a mosquito repellent. This prevention is available in various sizes including 4-10lbs, 11-20lbs, 21-55lbs, and over 55lbs. Purchasing through Amazon you can buy this repellent 2 doses, 4 doses, or 6 doses at a time.

4. Bayer Advantage II Topical Flea Treatment

Price: $43.77Bayer Advantage II Topical Flea Treatment Dogs

Another product from Bayer Animal Health, Bayer Advantage II Topical Flea Treatment is designed to treat multiple life stages of fleas. An odorless and colorless formula, Advantage II also works against lice infestations. This treatment is available for dogs from 3-10lbs, 11-20lbs, 21-55lbs, and over 55lbs. You can purchase this treatment in 4 or 6 doses at a time.

5. Novartis Capstar Flea Tablets

Price: $25.99Novartis Capstar Flea Tablets for Dogs and Cats

A product of Novartis, Capstar is an oral flea control preventative designed to kill fleas within 4 hours of taking it. This is the best flea treatment for dogs, because it is capable of killing adult fleas and is available for dogs from 2-25 lbs. or dogs over 25 lbs. This treatment is sold as a box of 6 tablets and is effective in dogs and cats. Capstar should be used for the treatment of existing flea infestations rather than as a preventative treatment.

6. Vet's Best Flea and Tick Home Spray

Vet's Best Flea and Tick Home Spray for Dogs and HomePrice: $ 11.49

Vet's Best Flea and Tick Home Spray for Dogs and Home kills fleas, flea eggs, and ticks on contact but it does not utilize harsh chemicals. Using certified natural essential oils and plant-based ingredients, this formula also repels mosquitoes. Non-staining, this formula is safe to use on dogs aged 12 weeks or older and can also be used on upholstery, carpets, drapes, rugs, and dog beds to repel pests.

7. Frontline Plus Flea and Tick Control

Frontline Plus Flea and Tick Control for DogsPrice: $56.98

Frontline Plus Flea and Tick Control for Dogs is a fast-acting treatment and preventative that kills ticks, lice, fleas, flea eggs and larvae to stop and prevent further infection. A single dose is effective for 30 days and one box contains 6 doses for half a year’s protection for your dog. This formula is a waterproof spot treatment.

8. Bayer Seresto Flea and Tick Collar

Bayer Seresto Flea and Tick CollarPrice: $54.99

The Bayer Seresto Flea and Tick Collar is approved for dogs from 7 weeks onwards and provides 8 months of protection against fleas, lice, and ticks. Through the continuous release of a low concentration of non-greasy, odorless protection, this best flea treatment for dogs are a long-term solution to prevention. The Seresto collar has also been shown to aid in the treatment of sarcoptic mange.

9. Lanalux Essential Oil Pest Control Collar

Price: $17.77Lanalux Essential Oil Pest Control Collar

Another preventative collar, the Lanalux Essential Oil Pest Control Collar offers 8 months of protection against fleas, ticks, larvae, lice, and mosquitoes. Using natural plant extracts, this is an all-natural and eco-friendly waterproof solution to pests. A one size fits all collar, this is a great solution for dogs that are prone to allergies or medication sensitivities.

10. Govesta Flea & Tick Collar

Price: $24.99Govesta Flea & Tick Collar for Dogs

Another flea and tick prevention collar, the Govesta collar provides 8 months of hypoallergenic waterproof protection against pests. This one size fits all collar is available in sizes for cats and dogs and protects against fleas, ticks, larvae, lice, and mosquitoes! Fully adjustable to fit any dog breed, this collar also comes with a 100% risk-free satisfaction guarantee for the first 30 days.

11. PetArmor Flea & Tick Treatment

Price: $9.69PetArmor Flea & Tick Treatment for Dogs

PetArmor Flea & Tick Treatment for dogs is designed to protect against fleas, ticks, and lice. This fast acting and waterproof spot treatment uses Fipronil to protect your dog from pests for 30 days. Sold in packs of three applications, this best flea treatment for dogs is available for 5 to 22 lb. dogs and for 44 lbs. and heavier dogs.

12. Advecta II Flea Treatment

Advecta II Flea TreatmentPrice: $19.99

Designed to kill fleas in their adult, larvae, and egg stages and chewing lice, this more affordable flea treatment contains the same active ingredients as Bayer Advantage II. This waterproof formula is sold four doses at a time and is available for dogs 3-10lbs, 11-20lbs, 21-55lbs, and over 55lbs.

13. Paws & Pals Natural Dog-Shampoo

Paws & Pals Natural Dog-Shampoo And ConditionerPrice: $14.95

Paws & Pals Natural Dog-Shampoo and Conditioner is a moisturizing, deodorizing, and detangling shampoo and conditioner that protects against fleas and ticks. Made with all-natural ingredients this shampoo is safe, non-toxic, and free of parabens. Oatmeal and shea butter provide nourishment and protection for even the most sensitive skin in this best flea treatment for dogs.

14. PetArmorPro Advanced

PetArmorPro AdvancedPrice: $19.95

Designed to kill and repel fleas, ticks, and lice as well as control mite infestations, PetArmorPro begins working within 24 hours. Safe for puppies older than 8 weeks old, this is a monthly topical treatment that is sold in boxes of three applications.

15. PetSupply Collar Flea and Tick Prevention

PetSupply Collar Flea and Tick PreventionPrice: $19.95

The PetSupply collar is designed to provide 8 months of protection against fleas, ticks, lice, and flea larvae. Made of non-toxic material, this is a safe and allergy-free collar that offers a one size fits all solution that can be trimmed to fit small, medium, and large dogs. This prevention option comes with a 1-year free replacement guarantee.

16. Waterproof Flea & Tick Collar

Waterproof Flea & Tick Collar For Dogs by Frankie Bee CompanyPrice: $15.95

The Frankie Bee Company waterproof flea and tick collar for pets is a safe alternative to flea and tick treatments. Designed to protect against fleas, ticks, flea larvae, lice, and mosquitoes. Active for up to 8 months of treatment, this best flea treatment for dogs is waterproof and comes with a 100% money back guarantee.

17. Wondercide Natural Flea & Tick Control

Wondercide Natural Flea & Tick Control for Pets and HomePrice: $12.99

Wondercide Natural Flea and Tick control for pets and home is a natural alternative to repel fleas, ticks, and mosquitoes as well as eliminate the full flea lifecycle. Recommended by holistic veterinarians, this formula is safe for puppies, adults, and seniors and can be used on your pet as well as bedding, carpet, rugs, and drapes.

18. Hartz UltraGuard Plus Flea & Tick Drops

Hartz UltraGuard Plus Flea & Tick DropsPrice: $12.49

Hartz UltraGuard Plus Flea & Tick Drops are an affordable solution to fleas, ticks, and mosquitoes as well as flea eggs and larvae. A single pack comes with three applications and each application lasts for 30 days. This best flea treatment for dogs is only to be used on dogs 12 weeks or older and is available in four sizes that treat dogs from 5 to 150 lbs.

19. PetArmor FastCaps

PetArmor FastCapsPrice: $13.29

PetArmor FastCaps are designed to rapidly kill fleas and eliminate flea infestations. A fast-acting oral medication, this formula has been approved by the FDA and eliminates adult fleas. Each pack contains 6 tablets and can be purchased for pets from 2-25lbs. or 25lbs+. A single dose can eliminate up to 90% of an infestation.

20. Adams Plus Flea & Tick Shampoo

Price: $10.60Adams Plus Flea & Tick Shampoo

Adams Plus Flea & Tick Shampoo with Precor for Dogs and Cats is designed to kill fleas, ticks, flea eggs, flea larvae, and lice. One application can provide 28 days of control against pre-adult fleas. Added aloe, coconut extract, oatmeal, and lanolin provide soothing relief while moisturizing skin. This shampoo also contains a pest growth regulator to prevent fleas from growing into their adult form.

21. Bio Spot Active Care Flea & Tick Spot On

Bio Spot Active Care Flea & Tick Spot OnPrice: $12.42

Bio Spot Active Care Flea & Tick Spot On With Applicator is designed to kill fleas, flea eggs, flea larvae, tick nymphs, and tick larvae as well as mosquitoes. This best flea treatment for dogs is available in 1 month, 3-month and 6-month supplies for dogs from 5 to 150 lbs. Bio Spot comes with a unique applicator for easy application and dries quickly once applied to your dog.

22. GreenPet All-Natural Flea and Tick Prevention

GreenPet All-Natural Flea and Tick Prevention and Control SprayPrice: $16.99

Dr. GreenPet All-Natural Flea and Tick Prevention and Control Spray provides maximum protection against fleas and ticks through premium quality essential oils. Unlike other preventatives, this spray has a pleasing scent and does not utilize any harsh chemicals. This preventative also eliminates flea eggs on contact and repels mosquitoes. This formula is made in the USA exclusively for your peace of mind.

23. VetriScience Laboratories Flea + Tick Defense

Price: $15.47VetriScience Laboratories Flea + Tick Defense

VetriScience Laboratories Flea + Tick Defense is a topical flea and tick repellent. Fast acting and long lasting, this waterproof formula also eliminates chewing lice. This preventative utilizes the same active ingredient as Frontline Top Spot but is more economical and has been shown to help to control sarcoptic mange. A single box contains three doses.

24. Wahl Dog/Pet Shampoo

Price: $16.19Wahl Dog/Pet Shampoo

This is the best flea treatment for dogs because it provides a defense against fleas and ticks through the natural properties of rosemary and mint. PEG-80 free, this shampoo is pH balanced, paraben free, and formulated without alcohol. Compared to other shampoo options, this Wahl formula comes in a larger bottle that gives you 70% more baths per bottle. The ingredients in this shampoo are all naturally derived.

25. Mercola Flea and Tick Defense

Price: $21.45Mercola Flea and Tick Defense

Dr. Mercola Flea and Tick Defense is a spray formula that provides natural flea and tick control through the use of essential oils. Made with lemongrass, cinnamon, sesame, and castor essential oils, this spray has no synthetic ingredients and can be used daily. In addition to protecting against fleas and ticks, this formula also protects against mosquitoes and other common pests as well.

26. Vectra 3D

Price: $69.87Vectra 3D

Recommended for use on dogs 8 weeks old and over, Vectra 3D is a fast-acting formula that begins acting within 5 minutes of application. Broad spectrum protection repels and kills fleas, ticks, mosquitoes, biting flies, sand flies, lice, and biting mites. A single topical application of this best flea treatment for dogs provides month-long protection, and each box comes with 6 months-worth of prevention.

27. Dog MD Max Defense Flea & Tick Topical

Price: $33.99 + $4.99 shippingDog MD Max Defense Flea & Tick Topical

Dog MD Max Defense Flea & Tick Topical for Dogs is a waterproof preventative formula that kills fleas, ticks, and chewing lice. Approved for use on dogs over 8 weeks old, this preventative uses the same active ingredient as Frontline products but is a more affordable solution. At the price noted above, you will receive six months’ worth of applications.

28. Sentry Fiproguard Plus for Dogs

Price: $15.00 + $4.99 shippingSentry Fiproguard Plus for Dogs

Sentry Fiproguard Plus for Dogs uses the same ingredients as Frontline Plus to kill fleas, flea eggs, flea larvae, ticks, and chewing lice. A single application protects your dog for 30 days and stops the flea life cycle and kills flea eggs and larvae for up to 3 months. This waterproof preventative is sold in 3 and 6 packs and is available for dogs from 4 to 132 lbs.

29. Honeydew Natural Pet Spray

Price: $9.95Honeydew Natural Pet Spray for Dogs & Cats

Honeydew Natural Pet Spray for Dogs & Cats is a two in one cleansing and grooming spray that naturally repels pests through essential oils. Lemongrass and citronella are gentle on your pet’s skin and safe for use without the negative side effects associated with chemical preventatives. Approved for daily use, Honeydew repels fleas, ticks, mosquitoes, and chiggers. Apply this preventative by spritzing your dog’s limbs and body.

30. PETnice Flea and Tick Prevention

Price: $20.99PETnice Flea and Tick Prevention for Dogs and Cats

A one size fits all solution to flea and tick prevention; this protective collar can be trimmed to size and provides 8 months of protection against pests. With proper use, this best flea treatment for dogs provides protection from insects, larvae, and eggs and is waterproof. A satisfaction guarantee provides peace of mind and long lasting protection makes for a budget-friendly solution to pest control.

31. Raw Paws Pet Organic Coconut Oil

Price: $13.99Raw Paws Pet Organic Coconut Oil for Dogs & Cats

Raw Paws Pet Organic Coconut Oil for Dogs and Cats is a 100% USDA certified organic oil with no GMO’s or pesticides that provides holistic relief for a host of problems. Not only does this oil provide relief for itchy skin, but it’s also effective in clearing up flea allergies, eczema, hotspots, and dermatitis and in preventing flea and tick infestations. Coconut oil is an economical all-purpose holistic treatment to have on hand.

32. Wondercide Natural Flea & Tick Bar

Price: $14.99Wondercide Natural Flea & Tick Shampoo Bar

Wondercide Natural Flea & Tick Shampoo Bar for Dogs & Cats is available in a single or double pack. Designed to cleanse your dog’s skin and coat while providing antibacterial and antifungal properties, this shampoo bar contains no chemicals, alcohol, artificial colors, or artificial fragrances. Made in the USA, this best flea treatment for dogs is a natural and organic option for killing and repelling flea and tick infestations.

33. TevraPet FirstAct Plus Flea and Tick Topical

Price: $16.99TevraPet FirstAct Plus Flea and Tick Topical for Dogs

TevraPet FirstAct Plus Flea and Tick Topical for Dogs is a single application preventative that protects your dog from fleas and ticks for 30 days after application. This waterproof formula utilizes the same active ingredient as Frontline Plus for Dogs but is a more economical solution with each box containing 3 months’ worth of protection. This preventative is available for dogs from 6 to 132 lbs.

34. Spuddy's Flea and Tick Prevention Collar

Price: $34.99Spuddy's Flea and Tick Prevention Collar

Spuddy's Flea and Tick Prevention Collar is a natural and hypoallergenic flea and tick preventative collar and drops kit. A single collar provides 6 to 8 months of protection through natural essential oils. Effective as soon as it is applied, this waterproof collar is 100% safe and non-greasy and has no scent to it. This preventative collar also protects against mosquitoes.

35. Novartis Parastar Plus for Dogs

Price: $46.00Novartis Parastar Plus for Dogs

Novartis Parastar Plus for Dogs is a topical application flea and tick preventative that provides protection for up to 30 days. Approved for dogs 8 weeks and older, this preventative protects against chewing lice as well as fleas and ticks and is fully waterproof. A single box contains three applications and is available for dogs from 4 to 132 lbs. Parastar is effective as soon as 1 hour after application.

36. DuckeBelle Flea and Tick Collar for Dogs

Price: $24.99Best Flea Treatments for Dogs

An all-natural flea and tick prevention collar, the DuckeBelle collar comes with one 24” length collar that can be trimmed to fit small, medium, and large breed dogs. One collar provides 4 months of protection without harsh odors while using non-toxic oils to repel pests. This best flea treatment for dogs also keeps lice eggs off your dog and is completely waterproof.

37. Field & Stream Dual Action Treatment

Field & Stream Dual Action Flea and Tick TreatmentPrice: $13.96

Field & Stream Dual Action Flea and Tick Treatment is designed to kill fleas, brown dog ticks, deer ticks, flea eggs, flea larvae, and to kill and repel mosquitoes. One application protects for 30 days and is approved for dogs aged 12 weeks and over. One box contains 3 tubes of preventative for 3 months of protection.

38. Sergeant's Pronyl OTC Max Drops

Price: $21.99Sergeant's Pronyl OTC Max Dog Flea and Tick Drops

Sergeant's Pronyl OTC Max Dog Flea and Tick Drops utilize the same active ingredient as Frontline products and starts killing fleas and ticks within an hour of application. A single application provides for 30 days of protection and one box of preventative provides three applications. This preventative is approved for dogs 12 weeks and older.

39. Bayer Defense Care

Price: $18.00Bayer Defense Care

Bayer Defense Care is a five-way protection preventative for dogs that protects against fleas, deer ticks, American dog ticks, brown dog ticks, and lone star ticks for up to 4 weeks at a time. This waterproof formula also repels and kills mosquitoes, biting flies, and chewing lice. This best flea treatment for dogs is recommended for dogs 7 weeks and older and each box contains 3 months of protection.

40. Provecta Advanced For Dogs

Price: $31.87Provecta Advanced For Dogs

Provecta Advanced for Dogs repels fleas, ticks, and mosquitoes, and kills chewing lice. Comparable to K9 Advantix II, this is a long-lasting and waterproof topical preventative that protects for up to 30 days. A single box of this best flea treatment for dogs contains four applications. Provecta is approved for dogs aged 7 weeks and older.

41. Durvet Adventure Plus for Dogs

Durvet Adventure Plus for DogsPrice: $29.06

Durvet Adventure Plus for Dogs protects against fleas, flea eggs, and flea larvae. A waterproof topical applicant, this preventative begins killing fleas within 12 hours of application and protects for up to 30 days. Approved for dogs 7 weeks and over and dogs of 3 lbs. or more, Durvet comes with four applications in a single box for four months of protection.

42. Adams Plus Flea and Tick Spray

Adams Plus Flea and Tick Spray for Cats and DogsPrice: $14.29

Adams Plus Flea and Tick Spray for Cats and Dogs is a spray formula that provides fast relief from biting fleas and kills adult fleas, flea eggs, flea larvae, and ticks. This best flea treatment for dogs also repels against mosquitoes. This formula is available in 16 oz. and 32 oz. bottles.

43. Maple Holistics Vanilla Oatmeal Shampoo

Price: $8.05Maple Holistics Vanilla Oatmeal Dog Shampoo with Lavender

Maple Holistics Vanilla Oatmeal Dog Shampoo with Lavender is a natural flea and tick preventative shampoo designed for dogs with sensitive skin. Colloidal oatmeal relieves skin irritation, lavender naturally repels fleas and ticks, and vanilla provides a soothing scent while restoring a sheen to your dog’s coat. Made in the USA, this best flea treatments for dogs is a hypoallergenic preventative with a 100% money-back guarantee.

44. PetAction Plus for Dogs

PetAction Plus for DogsPrice: $32.99

PetAction Plus for Dogs is designed to kill fleas, flea eggs, flea larvae, ticks, lice, and mites. Fast acting and long lasting, this topical formula also provides protection against mosquitoes and keeps your dog protected for 30 days with one application. For the price noted above you will receive 6 months of preventative.

45. Gold Medal Pets Shampoo

Gold Medal Pets Shampoo for DogsPrice: $10.99

Gold Medal Pets Shampoo for Dogs kills fleas, ticks, and lice while adding luster to your dog’s coat. Applied every 2 weeks, this one of the last best flea treatment for dogs options offers ongoing protection against pests for dogs 12 weeks and over. The brand itself has been well-rated and regarding by pet owners of both dogs and cats, and maintained a good success ration according to Amazon reviews and responses on dog forums.

46. Terra Pet Naturals 100% Repellent Spray

Price: $18.99Terra Pet Naturals 100% Natural Flea and Tick Repellent Spray

Terra Pet Naturals 100% Natural Flea and Tick Repellent Spray for Dogs and Puppies is an all-natural and organic preventative. Designed to prevent and control fleas, ticks, and other pests, this preventative relies on all-natural essential oils and apple cider vinegar. Safe for dogs with sensitive skin, this preventative is recommended for dogs aged 8 weeks and over and is simply sprayed onto your dog’s coat.

47. EcoFlea All-Natural Flea Prevention

EcoFlea All-Natural Flea Prevention Dog Treat by Colorado Dog CompanyPrice: $22.50

EcoFlea All-Natural Flea Prevention Dog Treat by Colorado Dog Company is a unique flea and tick preventative that comes in treats! An all-natural formula, EcoFlea is a safe alternative to flea and tick control that is produced in the United States. Garlic powder and brewers yeast come together in these tasty treats to offer a less toxic method of protection against pests.

48. Natural Care Flea and Tick Spray

Price: $8.97Natural Care Flea and Tick Spray for Dogs and Cats

Natural Care Flea and Tick Spray for Dogs and Cats is a natural spray preventative that kills fleas, flea eggs, and ticks on contact. This preventative also repels mosquitoes. With no harsh chemicals, this preventative uses all-natural plant extracts to keep pests at bay. Made in the USA, this spray is safe to use around the whole family and doesn’t stain upholstery or fabric.

49. Northern Pet Natural Flea & Tick Control

Price: $18.95Northern Pet Natural Flea & Tick Control Spray For Dogs and Home Use

Northern Pet Natural Flea & Tick Control Spray For Dogs and Home Use is an all-natural spray preventative designed to kill fleas, flea eggs, and ticks as well as repel mosquitoes. Peppermint, cloves, and cinnamon oils protect your dog without any harsh chemicals and is safe to use inside the home and on your dog’s coat. This is a non-staining spray formula that is approved for dogs aged 12 weeks and older and it is made and bottled in the USA.

50. TevraPet Activate II Flea and Tick Topical

Price: $24.01TevraPet Activate II Flea and Tick Topical

TevraPet Activate II Flea and Tick Topical relies on the same active ingredients as K9 Advantix II for Dogs. Designed to repel fleas, flea eggs, ticks, biting flies, and mosquitoes, this formula is made in the USA. Providing waterproof protection for 30 days at a time, each box of preventative contains 4 months-worth of protection.

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