The Mastiff dog breed is an elegant, gentle giant. They are also known as the Old English Mastiff.

This breed is one of the oldest dog breeds around and in this article, we'll discuss a few of the most popular mastiff mixes out there.

There are plenty of dog breeds that you can mix with the Mastiff. For instance, there's the Pitbull Mastiff mix, the Great Dane mastiff mix, and the Boxer Mastiff mix.

But before we get into the different mastiff mixes, let's have a quick background check on the Mastiff dog breed.

best dog food for Mastiffs

Mastiff Dog Breed

The Mastiff dog breed is one of the most ancient types of dog breeds. They make great companions for people who can accommodate their big size.

We do not recommend adopting this kind of dog breed if you're living in a small apartment or are a first-time dog owner. But if you're fond of big and loveable dogs, the Mastiff dog breed might be the dog for you.

Male Mastiffs can grow up to 32 inches and weigh between 160 to 230 pounds. On the other hand, female Mastiffs can measure 27 or 28 inches plus and weigh between 120 and 170 pounds. With that said, they are indeed massive dog breeds.

They are described as courageous and excellent watchdogs. But even though they are great watchdogs, they are rarely aggressive and would rather stand their ground, knowing that any strangers or intruders are not winning against them.

These dogs are the essence of what you call a gentle giant. However, some Mastiffs tend to be lazy dogs.

Don't be swayed by their cuteness. You must get them moving every day for the betterment of their health.

Without further ado, let's talk about different kinds of Mastiff Mixes.

10 Different Mastiff Mixes

Mastador (Mastiff + Labrador)

  • Height: 28 – 36 inches
  • Weight: 85 – 160 pounds
  • Lifespan: 10 -12 years

Temperant of Mastadors

First on our Mastiff Mixes list is the Mastador. This is a mix of Mastiff and the Labrador. Sweet as cinnamon but is on their guard to protect you.

The Matador is a family-guard dog kind of fellow. From both of their origin breed, they’re very family-oriented but are sensitive enough to stay alert with strangers and other dogs.

Mastador is perfect for homes with experienced owners since their big stature might be too much to handle children, and they may need supervision around them. Other than that, Matadors can make great watchdogs, too.

They’re flexible and quite great at training but at times stubborn. Mastadors need early socialization and basic training since if they are mishandled, they may become timid and aggressive. 

Possible Health Problems

Sadly, there are several diseases that Mastador has inherited from its breed origin. 

Mastiff Labrador Mix

Mastibull (Mastiff + Bulldog)

  • Height: 28 – 32 inches
  • Weight: 100 – 130 pounds
  • Lifespan: 8 – 10 years

Temperant of Mastibulls

Mastibulls are like those big brown bears. They’re a mix of Mastiff and Bulldog.

Mastibulls are very fond of their family—maybe a little bit too much that they can become overprotective.

They’re very affectionate toward their owner and family and even treat the children like their own.

A hint of brawling instinct may seep out if they don’t get the proper training and early-continuous training they need.

So, strangers and other animals should be introduced carefully and slowly. Display of security and comfort can help them feel at ease.

They may also forget how big they are and may still consider themselves lapdogs even when they’re older. Big softies, aren't they?

Possible Health Problems

Sadly, there are several diseases that Mastibull has inherited from both its breed origin. Here are the diseases owners should look out for:

  • Bloat / Gastric Dilation Volvulus
  • Cataracts
  • Canine Hip Dysplasia
  • Demodectic Mange
  • Hypothyroidism
  • Progressive Retinal Atrophy
  • Seizure

Mastiff American Bulldog Mix

  • Height: 23 – 29 inches
  • Weight: 100 – 150 pounds
  • Lifespan: 10 – 12 years

Temperant of Mastiff Bulldogs

They take guardianship of the family to the next level. Their affection towards their family may be big, but their desire to keep them from harm and danger is bigger.

Yes, Mastiff American Bulldog Mix is loving and protective of their family. They’re quite vigilant around strangers and other animals, so continuous training and socialization are a must for this breed.

Training should not be just early but continuous; this breed is quite stubborn due to its intelligence. Utilizing their protective nature and intelligence in training and exercise can reduce stubbornness.

Not to mention, they’re velcro dogs, so they’re best with families who are home all the time, or at least they have company most of the time. 

This mixed breed has a strong sense of protection and often may overpower its owner when it comes to safety. 

Possible Health Problems

There are several diseases that Mastiff American Bulldog Mix may have inherited from both its breed origin. Determining will be done through consultation and testing during their visit with the veterinarian.

Boxer and a English bull Mastiff running

Mastiff Shepherd (Mastiff + German Shepherd)

  • Height: 25 – 30 inches
  • Weight: 120 – 190 pounds
  • Lifespan: 8 – 12 years

Temperant of Mastiff Shepherds

Friendly giants they are! Mastiff Shepherds is a cross between a German Shepherd and a Mastiff.

They aren’t just affectionate but social butterflies, too. They want to be involved with everything and everyone they’re around it.

They’re very affectionate and have much of velcro tendencies toward their families as well. Mastiff Shepherds are great with children as well, just a minimal precaution and supervision.

They need some introduction to new people before they open up. They also do well with other animals as well.

Of course, early socialization and training are needed to further influence their personality. Mastiff Shepherds are incredibly intelligent.

They may not be as active, but if the activity requires mental stimulation, they’ll be giddy and excited to join. 

Possible Health Problems

Sadly, there are several diseases that Mastiff Sheperd may have inherited from their breed origin. These are the following owners should look out for:

  • Bone Cancer
  • Diabetes
  • Eye Problems
  • Urinary Tract Infections
  • Hip Dysplasia

Mastweiler (Mastiff + Rottweiler)

  • Height: 25 – 30 inches
  • Weight: 100 – 150 pounds
  • Lifespan: 8 – 12 years

Temperant of Mastweilers

Mastweiler is a great family dog. It is a cross between a Mastiff and a Rottweiler.

They treat children as their own and protect them, but of course, supervision is needed. However, they may become overprotective, so exposing them to different things may help lessen that trait.

Strangers and other dogs may need some gradual and proper introduction, especially when they’re around their family, as they become extra protective. Mastweilers are not best with small animals as they have the instinct to hunt after them.

Since Mastweillers are closer to their hunting history, exposing them to early-continuous training and proper exercise may regress their aggressive tendencies.

Possible Health Problems

Mastweilers may need some precautions regarding their health. There are several health conditions they may have trouble with.

Since both origin breeds have different health backgrounds as well. Here are the following to look out for:

  • Bloat
  • Elbow and Hip Dysplasia
  • Eye Problems
  • Hypothyroidism
  • Obesity
  • Osteosarcoma
  • Stenosis

Boxmas (Mastiff + Boxer)

  • Height: 23 – 36 inches
  • Weight: 70 – 100 pounds
  • Lifespan: 10 – 13 years

Temperant of Boxmas

The Boxmas’, Boxer and Mastiff Mix Breed, temperament may depend on which of its origin breed will it inherit. Often Boxmas are quite full of humor and affection towards their owner or family, they love entertaining their family as much as spending time with them.

They’re also jolly, energetic, intelligent, and protective too. They may tend to choose an owner from their family.

It’s best to have the family distribute food-grooming regimens so Boxmas won’t get too familiar with only one member.

Other than that, they make great family dogs and can open up to strangers as they’re quick to determine if the stranger is safe or not. Boxmas do need early socialization and basic training to influence their behavior. 

Possible Health Problems

Sadly, there are several diseases that Boxmas may have inherited from their breed origin. 

  • Hip Dysplasia
  • Intervertebral Disc Disease

Boxer Mastiff Mix

Mastiff Husky Mix (Mastiff + Siberian Husky)

  • Height: 20 – 25 inches
  • Weight: 50 – 110 pounds
  • Lifespan: 10 -12 years

Temperant of Mastiff Huskies

The Mastiff Husky Mix is great as a family dog. They can bond well with their owners, families, and children as well. They can be good around other animals as long as they were exposed socially when they were young.

Mastiff Husky Mix is quite an intuitive breed, a clear and firm leadership is what they need to thrive. They’re quite independent so they may become stubborn unless their owner is firm with them.

Other than that, the Mastiff Husky Mix is an amazing companion. Smart, loyal, and loving!

Possible Health Problems

Mastiff Husky Mix is observedly healthy, but precautions for owners since mix breeds do not ultimately remove the inherited disease. Here are the following owners should look out for:

  • Cardiomyopathy
  • Entropion
  • Hip Dysplasia

Mastidoodle (Mastiff + Poodle)

  • Height: 25 – 36 inches
  • Weight: 90 – 140 pounds
  • Lifespan: 8 – 10 years

Temperant of Mastidoodles

Giants for cuddles and protection? Mastidoodle is the one for you! The Mastidoodle is a cross between a Poodle and a Mastiff.

Looking for gentle giants that are capable of protecting your family and staying by their side? Maltidoodle is the one for you!

Maltidoodles make great watchdogs. They’re very protective of their owner and family and will voluntarily guard them.

They’re also very affectionate to their family and children, and they’re great cuddle-buddies, too.

Supervision is still required, of course, and their huge stature may still need some assistance as they love responding to cuddles with cuddles.

Maltidoodles are on the active side, too! So spending time with them through a variety of activities is a blast.

Mastidoodle may need early socialization and training. They’re quite quick-witted and may get bored with repetitive exercises and training drills, so maybe making it different once in a while will get their attention.

Maltidoodle has velcro tendencies. They may be vigilant around new people and animals, but a little introduction and safety check will reassure them that there’s no danger involved!

Possible Health Problems

Sadly, there are several diseases that Mastdoodle has inherited from both its breed origin. Here are the diseases owners should look out for:

  • Cataracts
  • Canine Hip Dysplasia
  • Entropion
  • Hypothyroidism
  • Progressive Retinal Atrophy
  • Seizure

Mountain Mastiff (Mastiff + Bernese Mountain Dog)

  • Height: 28 – 38 inches
  • Weight: 150 – 200 pounds
  • Lifespan: 7 – 12 years

Temperant of Mountain Mastiffs

Last on our Mastiff Mixes list is the Mountain Mastiff is a cross between a Mastiff and a Bernese Mountain Dog.

These dogs can be easily mistaken for a Saint Bernard or a chonky or fluffy mastiff, but the Mountain Mastiff is a unique mix that can be a new part of your family.

They are loving, kind, and sensitive dogs. Just like the Mastiff, they are gentle giants with an even temperament that allows them to do well with children and other pets.

They have a natural wariness of strangers while having the eagerness to please their humans. Just like any other dog, training is required to be knowledgable and should be done in a positive way for them to learn quickly.

Possible Health Problems

Unfortunately, there are several diseases that the Mountain Mastiff has inherited from both its breed origin. Here are the diseases owners should look out for:

  • Elbow Dysplasia
  • Progressive Retinal Atrophy
  • Hip Dysplasia
  • Von Willebrand's Disease

Daniff (Mastiff + Greate Dane)

  • Height: 23 – 33 inches
  • Weight: 115 – 190 pounds
  • Lifespan: 8 – 10 years

Temperant of Daniffs

Friendly potato couch? Well, that’s the Daniff for you. The Daniff is a mix of Great Dane and Mastiff.

Daniffs love to spend time relaxing with their owners or families, and outdoor exercises are also thrilling for the heart.

They are good with children but supervision is still a must, these fellas are quite big, so it’s just a precaution. Daniffs are less vigilant than other Mastiff breeds, but they will warn their owners when they feel unsafe or strange around a stranger or in a situation.

The Daniff is very intelligent so training might need a little more effort than needed. They can’t work for what you want unless it’s more for them so maybe put up a trick with a delicious treat or two. 

Possible Health Problems

Sadly, there are several diseases that Daniff may have inherited from their breed origin. The tests can be done before breeding to avoid litter to obtain the diseases.

  • Bloat
  • Cancer
  • Hip Dysplasia

Great Dane Mastiff Mix

Frequently Asked Questions About Mastiff Mixes

Do Mastiffs bark a lot?

If you're not fond of excessive barking, Masttifs might be the dog for you. Mastiffs are calm, quiet, and well-mannered.

And even though they are great watchdogs, they do not bark as much as other watchdog breeds.

Are Mastiffs easy to train?

Mastiffs are the type of dogs that you'll enjoy training because of their eagerness to please. They are known to be a soft breed.

However, keep in mind that you should use positive reinforcement when it comes to training, as these dogs don't respond well to scolding or negative training tactics.

Which is bigger, a Mastiff or a Bullmastiff?

Overall, both of these dogs are massive. But between a Mastiff and a Bullmastiff, the English Mastiff is bigger.

Male Bullmastiff can reach about 25 to 27 inches, while females can reach between 24 to 26 inches. On the other hand, English Mastiffs stand at 30 inches tall or more, while females are at 27 inches tall.


Mastiff Mixes: 10 Different Massive Crossbreeds Summary

Overall, some of these Mastiff Mixes are fun, some are loving, some are protective, and some are relaxed. But whatever mixed breed you choose, keep in mind that they are all well-mannered and good-natured dogs.

If you're planning to adopt a mastiff mix in the future, you must first make sure that your home is big enough to handle these kinds of dogs. Remember that these mixes are massive and will not fit in a tiny apartment.

Also keep in mind that even though some of the mixes do not require a lot of exercises, it is still important to still keep them moving for the sake of their health.

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