Science-based Ways to Relieve Anxiety in Dogs

Some may believe that the feeling of anxiety is confined only to humans. They would be wrong.

The feeling of worry, nervousness, and unease extends to man’s best friend as well.

If your Fido suffers from this condition, learning to relieve anxiety in dogs with these science-based methods will make life much easier for you and your pup.

Dogs have been observed to display the same kinds of behavior and actions associated with humans suffering anxiety attacks.

And, much like humans, certain protocols, treatments, and actions can be done to decrease or even do away with the effects of anxiety.

Many owners don't even realize that their dog has anxiety. If you notice signs like:

  • excessive barking or howling
  • panting
  • drooling
  • pacing
  • shaking

…your dog may be suffering from anxiety. Certain types of anxiety in dogs, like the infamous separation anxiety, are easy to figure out.

When you leave the house, your dog becomes anxious and may bark, howl, or become destructive.

Sometimes, this can be relieved with a simple dog anxiety vest, petting and spending time with a dog, or going the over-the-counter dog anxiety aids route.

But other triggers of anxiety in dogs may be more difficult to pinpoint and even harder to deal with and relieve in canines.

Regardless of what may be causing the issue, you need to know how to relieve anxiety in dogs in order to help your pooch.

In this article, I'm listing ten of the best methods that have science-based roots and have been proven to work, so it is very likely that one or more will work to help ease your dog's anxiety too.

RELATED: 4 Factors That Cause Anxiety In Dogs (According To Research)

10 Science-based Ways to Relieve Anxiety in Dogs


1 Desensitization or Counter-Conditioning

Studies on the introduction and elimination of neuroses in animals show that fear, anxiety, and other undesirable behaviors are persistent habits that occur through learning (Wolpe, 1961).

One effective method to successfully un-teach an undesirable behavior in animals is counter-conditioning.

Counter-conditioning is training the dog to behave positively in place of negative behavior (such as fear or anxiety).

Repeatedly feeding your dog while it is responding to a stimulus that elicits weak anxiety, then slowly increasing to a strong stimulus, may be successful in reducing anxiety.

Each time the animal is exposed to food, the anxiety response becomes inhibited and is replaced with positive responses associated with eating.

On the other hand, desensitization is the repeated, controlled exposure of the stimulus that usually elicits fear or anxiety in your dog so that your dog no longer has the undesirable response.

When owners were provided a desensitization program for their pets, dogs showed a decreased fear of loud noises, such as fireworks (Levine et al. 2007).

In addition, systematic desensitization was found to be a successful treatment for dogs with separation-related anxiety (Butler et al., 2011).

2 Exposure to Different Social Situations and Environments as Puppies

Exposing puppies to various situations and environments when they are still young will reduce the chances of them exhibiting fearful behavior. Deprivation of experiences can make young dogs habitually fearful and anxious.

Training and learning during early life are critically important for learning appropriate behaviors.

For example, studies on rats and dogs show that restricting early experience (Thompson et al. 1954), such as removal of an enriched environment and learning new things, will result in better behavior, learning ability, and intelligence as adults.

Exposure to an enriched environment may also prevent the animal from being anxious or fearful of different stimuli.

In Scottish terriers, animals that were restricted in early experiences show that there is a deficit in problem-solving ability and a retarding effect on intelligence at maturity.

Exposure to different environments can be a learning experience in early life and can also contribute to the dog’s personality, such as emotional behaviors, fears, and anxiety (Hebb, 1955).

ALSO READ: 7 Proven Ways to Calm Down A Dog (Backed by Science)

3 Pheromones

Synthetic pheromones, such as Dog Appeasing Pheromone (DAP) or Adaptil, mimic the natural pheromones that mothers release during nursing. It's one of the most studied methods to help anxious dogs today.

Dog Appeasing Pheromones can be sprayed around the house, or anywhere else your dog may be exhibiting anxious behavior. DAP is believed to make your dog feel safer and relaxed, resulting in very effective anxiety relief in dogs.

Pheromones, in general, can be used for general stress, separation anxiety, noise phobias, and travel.

A recent article we've published has analyzed more of the studies of dog-appealing pheromone collars for dogs and their proven effectiveness on anxiety in dogs.

In a study with 54 dogs that were afraid of fireworks, there was a significant improvement in total fear severity scores and global fear scores (Tod et al. 2005).

Some veterinary clinics use DAP in the waiting room to prevent anxiety and fear of dogs.

DAP resulted in greater relaxation of dogs in the clinic setting. In a shelter setting, DAP effectively reduced barking and other stress indicators in dogs (Mills et al. 2016).

4 Melatonin

Melatonin is a natural hormone that the body produces in the pineal gland that helps to control your sleep and wake cycle.

Melatonin is often used to calm nerves, reduce anxiety, and facilitate deep sleep.

Relieve Anxiety in DogsIn an animal model, melatonin was shown to exhibit anxiolytic activity (Papp et al. 2006).

In humans, an increase in melatonin secretion is associated with relaxation and decreasing anxiety and insomnia.

Melatonin at doses of 4 and 6 mg/kg was able to reduce anxiety elicited by injections of lipopolysaccharide (Nava et al. 2001).

The amygdala area of the brain may be involved in the beneficial effects of melatonin on anxiety.

When rats were administered melatonin in the amygdala, animals decreased behaviors of anxiety; however, spatial memory performance was negatively affected (Karakas et al. 2011).

5 Anti-anxiety Medications

Anti-anxiety medications are drugs that are useful for alleviating symptoms of anxiety and are typically used in combination with other types of therapy, including counter-conditioning and desensitization.

Some commonly used anti-anxiety medications for dogs include:

Alprazolam (Xanax): These are typically used for dogs with noise phobias and can reduce signs of anxiety, such as panting, pacing, trembling, hiding, excessive salivation, destructiveness, excessive barking, and self-trauma when given at a dosage of 0.02mg/kg 1 hour before an anticipated storm (Crowell-Davis et al. 2003).

Clonazapam (Klonopin): Can be used to relieve anxiety in dogs as well as seizure control (at higher doses) (Crowell-Davis et al. 2008).

Diazepam (Valium): 24% of owners who use diazepam to decrease fear and relieve anxiety in dogs during thunderstorms reported Valium was effective (Herron et al. 2008). However, some negative side effects of Valium include sedation, increased appetite, agitation, and aggression.

Clomipramine: Separation anxiety, obsessive-compulsive disorder, and noise phobia were effectively controlled with the use of another anti-anxiety medication called clomipramine (Seksel et al. 2001).

Trazodone hydrochloride: Enhances behavioral calming and relieves anxiety in dogs when administered daily or on an as-needed basis (Gruen et al. 2008).

6 Diet

If your dog’s diet consists mainly of junk food, he may become hyperactive or anxious.

Although not a lot of studies have looked at this relationship, a study of 4,000 children in the UK showed that diets high in junk food intake were associated with an increased level of hyperactivity by the age of 7 years old and were likely to fall in the top 33% of the hyperactivity scale (Wiles et al. 2007).

In contrast, polyunsaturated fatty acids, such as Omega-3 and Omega-6, can improve symptoms and help to relieve anxiety in dogs, including appetite, mood, poor sleep, attention, focus, and fatigue (Yehuda et al. 2013).

7 Bach Flower Remedies

Bach RESCUE REMEDY PET Dropper 20mL, Natural Stress Relief, Calming for Dogs, Cats, & Other Pets, Homeopathic Flower Essence, Thunder, Fireworks & Travel, Separation, Sedative-Free Bach flower remedies are a mixture of water, brandy, and dilutions of flower materials, including chicory, heather, red chestnut, and honeysuckle, that were originally developed by a renowned homeopath named Edward Bach.

It was thought that the flower petals have healing properties.

An example of a marketed Bach flower remedy is a product called Rescue Remedy, which contains five flowers.

In a double-blind clinical trial, Rescue Remedy was shown to decrease measurements of anxiety (Halberstein et al. 2007).

Although no formal experiments have been conducted on these herbal drops in animals, some dog owners attest to their ability to reduce anxiety.

INTERVIEW: How To Deal with Separation Anxiety in Dogs

8 Skullcap

Skullcap is a powerful medicinal herb that is grown in eastern North America and has been traditionally used to alleviate nervous tension exhaustion, as well as to promote relaxation (Brock et al. 2014).

Results from preliminary clinical research and in vitro studies are promising for the potential use of skullcaps for anxiety and anxiety-related disorders (Brock et al. 2010).

Skullcap is used to treat a wide range of nervous conditions, including insomnia, hysteria, and withdrawal.

It can also help to relieve anxiety in dogs and humans.

9 Valerian

Valerian, like skullcap, is an herb that has traditionally been used to treat insomnia, stress, and anxiety. In a study comparing the effects of valerian to anti-anxiety medications, they were comparable in relieving anxiety (Shahinfar et al. 2016).

Because valerian is a natural herb, it may be more beneficial to use instead of chemical medications to relieve anxiety in dogs.

However, Pet Remedy, a product containing Valerian, vetiver, basil, and sage, and applied via a spray, was shown not to reduce the stress response in dogs (Taylor et al. 2016).

This indicates that further research on valerian's ability to relieve anxiety in dogs is necessary.

10 Zylkene

Zylkene is a natural remedy that helps to relax and calm your pets, particularly in stressful situations, such as thunderstorms and a clinical environment.

The active ingredient in zylkene is a refined protein that is typically found in milk that stimulates receptors in the brain.

Numerous studies have looked at the effects of Zylkene.

Zylkene was effective in:

Anxiety in dogs may seem innocuous at first, but the cascade of emotions and actions that come after can have massive repercussions not only for the health of the dog but also the health of the relationship with its owner(s).

Thanks to medicines helping in treating anxiety in humans, combined with some canine-specific solutions, treatments now exist to ease the stress and relieve anxiety in dogs.

READ NEXT: 12 Signs Your Dog Is Stressed

10 Science-based Ways to Relieve Anxiety in Dogs

Mary has a Bachelor of Science in Biology and Neuroscience, and has been specializing in animal science writing for over ten years. She's very experienced in scientific reports, data analysis and science-based research, and obsessed with accurate information.